The Recall Desk
HighFDA (Drugs)·D-0632-2025·Announced 2025-09-17

Zydus chlorpromazine 25 mg tablets recalled over nitrosamine above intake limit

Zydus Chlorpromazine Hydrochloride Tablets, USP, 25 mg, are recalled nationwide because N-Nitroso Desmethyl Chlorpromazine was found above the recommended acceptable intake limit.

What this means for you

Real risk of harm even if no illness or injury has been reported yet. Stop using the product and follow the agency's guidance.

Our severity reasoning: Rubric level 3 covers risk-of-harm products where injury has not yet been reported; a nitrosamine above the recommended acceptable intake limit is a potential harm and no injuries are reported.

Plain-English summary

Chlorpromazine Hydrochloride Tablets, USP, 25 mg, in 100-count bottles and available on prescription only, manufactured by Zydus Lifesciences Ltd. in Baddi, India and distributed by Zydus Pharmaceuticals (USA) Inc. of Pennington, New Jersey, NDC 70710-1130-1, are being recalled. Affected lots include Z305060 and Z305061 expiring 31-08-25, Z306323 expiring 30-11-25, Z401153 expiring 28-02-26 and Z403015, with the full list in the recall notice. Distribution was nationwide.

The recall follows current good manufacturing practice deviations: the presence of N-Nitroso Desmethyl Chlorpromazine above the recommended acceptable intake limit. The FDA classified the action as Class II.

Patients should check the lot number on their bottle against the recall and should not stop taking a prescribed medicine without speaking to their pharmacist or prescriber about a replacement supply.

The recalled product

Product
CHLORPROMAZINE HYDROCHLORIDE (CHLORPROMAZINE HYDROCHLORIDE)
Brand
CHLORPROMAZINE HYDROCHLORIDE
Manufacturer
Zydus Pharmaceuticals (USA) Inc
Hazard
  • nitrosamine-impurity
  • cgmp-deviation
  • prescription-drug
  • class-ii

Is your product affected?

Check your packaging against the codes below. If any of them match, the product is part of this recall.

Lot numbers (12)

  • Lot #: Z305060
  • Z305061
  • Exp Date 31-08-25
  • Z306323
  • Exp Date 30-11-25
  • Z401153
  • Exp Date 28-02-26
  • Z403015
  • Z403016
  • Exp Date 30-04-26
  • Z405591
  • Exp Date 30-09-26

UPCs (3)

  • 0370710112912
  • 0370710113216
  • 0370710113018

Distribution

Distributed nationwide across the United States.