The Recall Desk
HighFDA (Drugs)·D-0361-2025·Announced 2025-04-16

Chlorpromazine Hydrochloride tablets recalled for excess chemical impurity

Zydus Pharmaceuticals is recalling Chlorpromazine Hydrochloride tablets (10 mg) due to elevated levels of N-Nitroso-Desmethyl Chlorpromazine impurity from manufacturing deviations.

What this means for you

Real risk of harm even if no illness or injury has been reported yet. Stop using the product and follow the agency's guidance.

Our severity reasoning: This FDA Class II recall involves a chemical impurity (N-Nitroso-Desmethyl Chlorpromazine) at levels above recommended limits. No illnesses or injuries have been reported. The hazard is present but unrealized, placing it in the "risk-of-harm products where injury has not yet been reported" category per the rubric.

Plain-English summary

Zydus Pharmaceuticals (USA) Inc. is recalling Chlorpromazine Hydrochloride Tablets, USP 10 mg due to manufacturing deviations that resulted in elevated levels of N-Nitroso-Desmethyl Chlorpromazine impurity exceeding the recommended interim limit.

The affected product is packaged in bottles of 100 tablets under NDC 70710-1129-1, with lot number Z400069 and expiration date 12/31/2025. Approximately 3,144 bottles have been distributed nationwide.

No illnesses or injuries have been reported in connection with this recall. Consumers and healthcare providers should not use the affected product. Patients should consult their healthcare provider for guidance.

The recalled product

Product
CHLORPROMAZINE HYDROCHLORIDE (CHLORPROMAZINE HYDROCHLORIDE)
Brand
CHLORPROMAZINE HYDROCHLORIDE
Manufacturer
Zydus Pharmaceuticals (USA) Inc
Hazard
  • nitrosamine-impurity
  • manufacturing-deviation

Is your product affected?

Check your packaging against the codes below. If any of them match, the product is part of this recall.

Lot numbers (2)

  • Lot #: Z400069
  • Exp.: 12/31/2025

UPCs (3)

  • 0370710112912
  • 0370710113216
  • 0370710113018

Distribution

Distributed nationwide across the United States.