The Recall Desk
SevereFDA (Drugs)·D-0488-2025·Announced 2025-06-18

Sulfamethoxazole and Trimethoprim Tablets Recalled for Microbial Contamination

Amneal Pharmaceuticals is recalling Sulfamethoxazole and Trimethoprim Tablets (400 mg/80 mg) nationwide due to microbial contamination that may cause black spots on tablets. The contamination affects non-sterile products distributed across the USA.

What this means for you

Illness, injury, or structural failure has been reported. Stop using the product immediately and contact the manufacturer for a refund or repair.

Our severity reasoning: This recall is FDA Class I, which per the rubric requires a minimum severity score of 4 ("never go below 4"). Microbial contamination in a non-sterile oral drug product presents risk of serious adverse health consequences.

Plain-English summary

Amneal Pharmaceuticals, LLC is recalling Sulfamethoxazole and Trimethoprim Tablets, USP, 400 mg/80 mg, Rx Only. The tablets may exhibit black spots due to microbial contamination of the non-sterile products. Affected bottles include 100-tablet bottles (NDC 65162-271-10) and 500-tablet bottles (NDC 65162-271-50).

The contaminated lots are AM241019, AM241020 (expiration 06/30/2027), and AM241019A (expiration 06/30/2027). Approximately 6,396 bottles were distributed nationwide in the USA by Amneal Pharmaceuticals LLC, Bridgewater, NJ. The tablets were manufactured by Amneal Pharmaceuticals Pvt. Ltd. in Ahmedabad, India.

Patients who have this medication should contact their healthcare provider or pharmacist. Do not use the recalled tablets without consulting a healthcare professional first. Return the affected medication to the pharmacy where it was dispensed.

The recalled product

Product
SULFAMETHOXAZOLE AND TRIMETHOPRIM (SULFAMETHOXAZOLE AND TRIMETHOPRIM)
Brand
SULFAMETHOXAZOLE AND TRIMETHOPRIM
Manufacturer
Amneal Pharmaceuticals, LLC
Hazard
  • microbial-contamination

Is your product affected?

Check your packaging against the codes below. If any of them match, the product is part of this recall.

Lot numbers (4)

  • Lot #s: a) AM241019
  • AM241020
  • Exp. 06/30/2027 b) AM241019A
  • Exp 06/30/2027

UPCs (2)

  • 0365168211102
  • 0365162272109

Distribution

Distributed nationwide across the United States.

Same brand · SULFAMETHOXAZOLE AND TRIMETHOPRIM