The Recall Desk
SevereFDA (Drugs)·D-0359-2019·Announced 2018-12-05

Sandoz Losartan Potassium and Hydrochlorothiazide Tablets Recalled for NDEA Impurity

Sandoz is recalling Losartan Potassium and Hydrochlorothiazide tablets because FDA testing found the impurity NDEA above acceptable levels.

What this means for you

Illness, injury, or structural failure has been reported. Stop using the product immediately and contact the manufacturer for a refund or repair.

Our severity reasoning: The recall is classified as FDA Class II, which corresponds to a Severe severity score under the rubric for significant potential health risks.

Plain-English summary

Sandoz, Inc. is recalling Sandoz Losartan Potassium and Hydrochlorothiazide Tablets, USP 100 mg/25 mg, 1000-count bottles. The affected product is identified by Lot # JB8912 with an expiration date of 06/2020. The recall involves 170 HDPE bottles distributed in Ohio and Puerto Rico.

The recall was initiated due to Current Good Manufacturing Practice (CGMP) deviations. FDA laboratory testing confirmed the presence of the impurity N-nitrosodiethylamine (NDEA) in the active pharmaceutical ingredient (API) used to manufacture the product. The detected levels of NDEA exceeded the interim acceptable daily intake level of 0.083 parts per million.

Consumers and healthcare providers should stop using the affected medication and contact their healthcare provider for guidance on alternative treatment options. The product is prescription-only (Rx Only).

The recalled product

Product
Sandoz Losartan Potassium and Hydrochlorothiazide Tablets, USP 100 mg/25 mg, 1000-count bottles, Rx Only, Finished Drug Product Manufactured by: Lek Pharmaceuticals d.d. SI-1526 Ljubljana,Sovenia for Sandoz Inc., Princeton, NJ 08540, NDC 0781-5207-10.
Manufacturer
Sandoz, Inc
Affected units
170

Is your product affected?

Check your packaging against the codes below. If any of them match, the product is part of this recall.

Lot numbers (2)

  • Lot #: JB8912
  • Exp. 06/2020

Distribution

Distributed in 2 states: