The Recall Desk
HighFDA (Devices)·Z-1072-2025·Announced 2025-02-12

VNS Therapy Generators May Stop Delivering Stimulation Due to Component Failure

The SenTiva and SenTiva Duo vagus nerve stimulation generators may stop delivering therapy due to an internal mechanical component becoming stuck, causing potential loss of seizure and depression control.

What this means for you

Real risk of harm even if no illness or injury has been reported yet. Stop using the product and follow the agency's guidance.

Our severity reasoning: FDA Class II recall without reported illnesses or injuries. The hazard is theoretical—described with conditional language ('may stop,' 'may result')—and involves risk of therapy loss. Per the rubric, risk-of-harm medical devices without reported injury score at most 3.

Plain-English summary

The U.S. Food and Drug Administration is recalling the SenTiva and SenTiva Duo vagus nerve stimulation (VNS) generators, manufactured by LivaNova USA, Inc. These devices are implanted to treat epilepsy and depression.

The internal generators may stop delivering electrical stimulation due to an internal mechanical component that can become stuck in a closed position. This failure would prevent the device from delivering the therapy patients depend on.

Approximately 81,606 devices with serial numbers less than 500,000 have been distributed across the United States and internationally. If the device stops working, patients may return to baseline seizure frequency or depressive symptoms, and may require replacement surgery.

Patients with affected devices should contact their physician or LivaNova USA, Inc. to determine whether their device is impacted and discuss appropriate next steps.

The recalled product

Product
SenTiva, REF: 1000; SenTiva Duo, REF: 1000-D; Generators Part of the VNS Therapy System. Used for Vagus Nerve Stimulation (VNS).
Manufacturer
LivaNova USA, Inc.
Hazard
  • device-failure
  • therapy-loss
  • seizure-recurrence

Is your product affected?

Check your packaging against the codes below. If any of them match, the product is part of this recall.

Lot numbers (3)

  • REF/UDI-DI: 1000/05425025750405
  • 1000-D/05425025750528 All Serial Numbers less than 500
  • 000

Distribution

Distributed in 41 states:

  • AK
  • AR
  • AZ
  • CA
  • CO
  • CT
  • DE
  • FL
  • GA
  • IL
  • IN
  • KS
  • KY
  • LA
  • MA
  • MD
  • ME
  • MI
  • MN
  • MO
  • MS
  • NC
  • ND
  • NE
  • NJ
  • NM
  • NY
  • OH
  • OK
  • OR
  • PA
  • SC
  • SD
  • TN
  • TX
  • UT
  • VA
  • VT
  • WA
  • WI
  • WV