The Recall Desk
HighFDA (Drugs)·D-1344-2022·Announced 2022-08-24

FDA Recalls Neostigmine Methylsulfate Injectable Due to Contamination Risk

Nephron Sterile Compounding Center is recalling one lot of Neostigmine Methylsulfate Injection due to potential cross-contamination from product carryover during manufacturing. The recall affects 13,500 vials distributed nationwide.

What this means for you

Real risk of harm even if no illness or injury has been reported yet. Stop using the product and follow the agency's guidance.

Our severity reasoning: FDA Class II recall of sterile injectable medication with potential cross-contamination. Although no illnesses have been reported, this is a risk-of-harm product where contamination could cause patient harm, meeting the rubric criterion for High severity.

Plain-English summary

Nephron Sterile Compounding Center LLC is recalling Neostigmine Methylsulfate Injection, USP, 1 mg/mL in 3 mL unit-dose vials. The recall is due to potential cross-contamination from product carryover during manufacturing, which is a deviation from Good Manufacturing Practice (CGMP) requirements.

The affected lot is NE1057A, which expires 10/23/2022. A total of 13,500 vials were distributed nationwide in the United States. The product is a prescription medication supplied as a sterile injectable.

Those who may have received this product should verify the lot number and contact their healthcare provider or supplier for guidance regarding the recall.

The recalled product

Product
PF-Neostigmine Methylsulfate Injection, USP, 3 mg/3 mL (1 mg/mL), One 3 mL Unit-Dose Vial, packaged in 30 x 3 mL Sterile Unit-Dose Vials per carton, Rx Only, Nephron 503B Outsourcing Facility, 4500 12th Street Extension, West Columbia, SC 29172; NDC 69374-932-33
Manufacturer
Nephron Sterile Compounding Center LLC
Hazard
  • cross-contamination
  • manufacturing-defect

Is your product affected?

Check your packaging against the codes below. If any of them match, the product is part of this recall.

Lot numbers (2)

  • Lot: NE1057A
  • Exp. 10/23/2022

Distribution

Distributed nationwide across the United States.