The Recall Desk
ModerateFDA (Drugs)·D-1028-2022·Announced 2022-06-15

FDA Recalls Betamethasone Dipropionate Cream for Temperature-Abuse Storage Deviations

McKesson Medical-Surgical is recalling Betamethasone Dipropionate Cream USP 0.05% due to temperature-abuse cGMP deviations. The FDA Class II recall affects nationwide distribution.

What this means for you

Minor labeling or packaging issue, or a voluntary precautionary recall. Risk of harm is low but real — follow the manufacturer's instructions.

Our severity reasoning: FDA Class II classification without reported illnesses, injuries, or safety hazards. The temperature-abuse deviation affects medication stability and efficacy, representing a precautionary recall with theoretical risk rather than acute harm.

Plain-English summary

McKesson Medical-Surgical Inc. is recalling Betamethasone Dipropionate Cream USP, 0.05%, in 45-gram tubes (NDC 0168-0055-46 and related package codes), manufactured by Sandoz Pharma. This is a prescription topical corticosteroid.

The recall stems from cGMP deviations involving temperature abuse. Exposure to improper temperatures may compromise the stability and potency of the medication.

The product was distributed nationwide. McKesson Medical-Surgical has notified customers who received shipments during the affected distribution period. Customers have been provided specific distribution dates in their recall letters.

Patients currently using this product should contact their healthcare provider or pharmacist for guidance. Report any adverse effects to the FDA's MedWatch program.

The recalled product

Product
Betamethasone Dipropionate Cream USP, 0.05%, 45 grams tube, Rx only, MFG: Sandoz Pharma, NDC 0168-0055-46
Affected units
1

Distribution

Distributed nationwide across the United States.

Part of a larger recall action

This product is one of 130 recalled by Mckesson Medical-Surgical Inc. Corporate Office under a single FDA (Drugs) recall action. The agency files each product separately, so the size of the action is not visible from this page alone.

See all 130 products in this recall →