The Recall Desk
ModerateFDA (Drugs)·D-0544-2023·Announced 2023-05-03

DuPont Recalls Avicel PH-101 Microcrystalline Cellulose for Out-of-Specification Conductivity

DuPont Nutrition USA is recalling specific batches of Avicel PH-101 NF microcrystalline cellulose due to failed conductivity specifications. The pharmaceutical excipient was distributed in bulk to manufacturers in the USA and multiple international locations.

What this means for you

Minor labeling or packaging issue, or a voluntary precautionary recall. Risk of harm is low but real — follow the manufacturer's instructions.

Our severity reasoning: FDA Class III recall with out-of-specification conductivity results on a pharmaceutical excipient. No reported illnesses or injuries. Specification failures represent quality deviations but are lower-risk than direct contamination with reported harm, per rubric guidance that Class III recalls are typically scored 1–2.

Plain-English summary

DuPont Nutrition USA, Inc. is recalling specific batches of Avicel PH-101 NF, a microcrystalline cellulose excipient used in pharmaceutical formulations. Approximately 464,050 kg of the product in bulk containers were affected.

The recall was initiated due to out-of-specification conductivity results for the affected batches. Conductivity specifications help ensure the purity and quality of the excipient.

The affected batches were distributed nationwide in the USA and internationally to Malta, Canada, China, Peru, Mexico, Australia, Saudi Arabia, Spain, Dominican Republic, Puerto Rico, Singapore, Bangkok, Ireland, India, and Colombia. The specific batch numbers under recall are: 2173809472, 2173811313, P120834282, P120834305, P120834313, P120834324, P120834423, P120834437, P120834443, P120834478, 2173739298, 2173740020, 2173771315, P120834254, and P120834476.

The recalled product

Product
Avicel PH-101 NF, Microcrystalline Cellulose NF, Net Content/Gross Weight 50.0 KG / 54.5 KG bulk container, Manufactured by: DuPont Nutrition USA, Inc., 1301 Ogletown Road, Newark, DE 19711, USA; Manufactured in USA; Headquarters: DuPont Nutrition Biosciences ApS, Langebrogade 1,
Manufacturer
DuPont Nutrition USA, Inc
Hazard
  • quality-specification-failure
  • impurity

Is your product affected?

Check your packaging against the codes below. If any of them match, the product is part of this recall.

Lot numbers (15)

  • Batch Numbers: 2173809472
  • 2173811313
  • P120834282
  • P120834305
  • P120834313
  • P120834324
  • P120834423
  • P120834437
  • P120834443
  • P120834478
  • 2173739298
  • 2173740020
  • 2173771315
  • P120834254
  • P120834476

Distribution

Distributed nationwide across the United States.