The Recall Desk
HighFDA (Drugs)·D-0108-2026·Announced 2025-11-05

Desipramine Hydrochloride Tablets Recalled for Excess N-Nitroso Impurity

Heritage Pharmaceuticals is recalling 8,754 bottles of Desipramine Hydrochloride Tablets nationwide due to N-Nitroso Desipramine impurity exceeding acceptable daily intake limits.

What this means for you

Real risk of harm even if no illness or injury has been reported yet. Stop using the product and follow the agency's guidance.

Our severity reasoning: FDA Class II recall with no reported illnesses or injuries. The hazard is a chemical impurity (N-Nitroso Desipramine) exceeding regulatory limits, constituting a risk-of-harm scenario where injury has not yet been reported. This meets the rubric criterion for Score 3 (High).

Plain-English summary

Heritage Pharmaceuticals Inc is recalling certain lots of Desipramine Hydrochloride Tablets, USP, 25 mg, manufactured by USV Private Limited in Daman, India and distributed nationwide. Approximately 8,754 bottles are affected, including Lot 18035876 (expiration 12/31/2025) and Lot 18036909 (expiration 09/30/2026).

The recall is due to a Current Good Manufacturing Practice (CGMP) deviation: the affected lots contain an N-Nitroso Desipramine impurity at levels exceeding the permissible acceptable daily intake limit. N-Nitroso compounds are controlled by the FDA as potentially harmful chemical impurities.

No illnesses or injuries have been reported in connection with this recall.

The recalled product

Product
DESIPRAMINE HYDROCHLORIDE (DESIPRAMINE HYDROCHLORIDE)
Brand
DESIPRAMINE HYDROCHLORIDE
Manufacturer
Heritage Pharmaceuticals Inc
Category
Drug
Hazard
  • n-nitroso-impurity

Is your product affected?

Check your packaging against the codes below. If any of them match, the product is part of this recall.

Lot numbers (3)

  • Lot#: 18035876
  • Exp Date: 12/31/2025 Lot#: 18036909
  • Exp Date: 09/30/2026

UPCs (6)

  • 0323155579017
  • 0323155582017
  • 0323155578010
  • 0323155583250
  • 0323155581010
  • 0323155580013

Distribution

Distributed nationwide across the United States.